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desktop the flat, upper working surface of a desk. [4 definitions]
desktop publishing the creation and preparation of text and graphics for publishing using small computers.
desman either of two molelike aquatic mammals found in eastern Europe and western Asia that feed on insects and have webbed feet and a long snout.
Des Moines the capital of Iowa.
Desmond Tutu South African cleric and leader in the struggle against apartheid, who was awarded the Nobel Peace Prize in 1984 (b.1931).
desolate without those things necessary or desirable for life; bleak; barren. [6 definitions]
desolation the condition of a place or person that is desolate. [4 definitions]
despair the state of being completely without hope. [3 definitions]
despairing suffering from or showing despair.
despatch variant of dispatch.
desperado a daring or dangerous outlaw.
desperate having no regard for danger as the result of hopelessness or great need. [4 definitions]
desperately in a desperate way; with a sense of extreme urgency, need, or despair. [2 definitions]
desperation the feeling or condition of someone or something that is desperate.
despicable worthy of hatred or contempt; worthless; low.
despise to hate or feel contempt for.
despite notwithstanding; regardless of. [3 definitions]
despoil to forcefully take belongings or goods from; plunder.
despoliation the action of forcefully seizing goods or belongings. [2 definitions]
despond to become discouraged and have low spirits, as from loss of hope or courage.
despondency the condition of one who is dejected by hopelessness or loss of courage.