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Comprehensive
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insistent firm in requesting, demanding, or asserting; unyielding. [3 definitions]
in situ (Latin) in its original place.
insobriety lack of sobriety or moderation; intemperance.
insofar to such extent or degree (usu. fol. by "as").
in so far as to the extent that.
insolate to treat by exposing to sunlight, as for drying or bleaching.
insolation exposure to sunlight, as for drying, bleaching, or other treatment. [3 definitions]
insole the portion of a shoe that touches the bottom of the foot; inner sole. [2 definitions]
insolence rude or impudent behavior or speech. [2 definitions]
insolent rude, arrogant, or offensively forward in speech or manner.
insoluble impossible to dissolve, esp. in a given liquid. [2 definitions]
insolvable impossible to solve; insoluble.
insolvent incapable of paying debts or meeting liabilities; penniless; bankrupt. [3 definitions]
in so many words explicitly; precisely.
in someone's bad graces having the disfavor and disapproval of someone.
in someone's good graces having the favor and approval of someone.
insomnia difficulty in getting to sleep, esp. as a persistent problem.
insomniac a person who has chronic difficulty in getting to sleep. [3 definitions]
insomuch to such an extent or degree (usu. fol. by "that"). [2 definitions]
insouciant having no cares or anxieties; light-hearted; carefree.
in specie in coin. [2 definitions]