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irreversible impossible to reverse, turn back, or alter.
irrevocable impossible to take back, undo, or cancel.
irrigable able to be irrigated.
irrigate to water by artificial means, as by pumping and spraying, or by man-made channels from a natural source of water. [2 definitions]
irrigation the supplying of water to land by man-made means to aid in growing crops. [2 definitions]
irritability the quality or condition of being irritable or easily angered. [2 definitions]
irritable easily annoyed or angered. [2 definitions]
irritant causing or tending to cause irritation, esp. physical irritation; irritating. [2 definitions]
irritate to anger or annoy. [4 definitions]
irritated annoyed or made angry. [2 definitions]
irritating causing irritation; vexing; inflammatory.
irritation the act of irritating, or that which irritates. [3 definitions]
irrupt to burst in suddenly or forcefully. [2 definitions]
IRS abbreviation of Internal Revenue Service, the US government agency responsible for administering and enforcing federal tax laws and collecting federal taxes.
Is. abbreviation of "island" or "islands," or "isle" or "isles" (used in a proper name).
is 3rd person present sing. of be.
Isaac according to the Old Testament, the son of the patriarch Abraham and the father of Jacob and Esau.
Isaac Newton an English philosopher and mathematician who formulated the laws of gravity (b.1642--d.1727).
isagoge an introduction, as to a field of scholarly study or research.
Isaiah a major Hebrew prophet of the eighth century B.C. [2 definitions]
ischemia a localized stoppage of blood supply caused by a blockage in the bloodstream.