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off-key not on the right musical note or pitch; flat or sharp. [2 definitions]
off-licence (chiefly British) a shop that sells alcoholic beverages; liquor store.
off-limits not to be entered or patronized by a designated group, such as military personnel.
off-line not connected to or controlled by a central computer.
off-load to unload (a ship or airplane, or passengers or goods therefrom).
off plumb not truly vertical.
off-price designating the retail stores or outlets that sell name brands and other high-quality merchandise at a discount. [2 definitions]
offprint a reprint of an article or part of an article. [2 definitions]
off-putting (informal) tending to annoy or repel.
off-road of a type of vehicle used primarily for areas other than streets and highways, such as a dune buggy.
off-season a period of less frequent use, activity, or visitation. [2 definitions]
offset that which provides a counterbalance or compensation. [9 definitions]
offset printing a printing process in which the inked impression is made on a rubber roller or blanket, from which it is then transferred to paper; offset.
offshoot a branch or shoot from a main stem, as of a plant. [2 definitions]
offshore away from the shore. [4 definitions]
offside ahead of the ball or puck, or beyond the line or area prescribed by the rules of a sport such as hockey or football.
offspring the child, young, or descendant of a particular parent or ancestor. [2 definitions]
offstage not on the visible part of the stage; in the wings or backstage. [3 definitions]
off the air not broadcast on radio or television.
off the beaten path in a place difficult to reach or not often visited. [2 definitions]
off the beaten track in a place difficult to reach or not often visited. [2 definitions]