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Comprehensive
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sphere a round, three-dimensional geometric figure in which every point on the surface is an equal distance from the center. [6 definitions]
sphere of influence foreign territory over which a state or nation exerts cultural, political, economic, or military authority. [3 definitions]
spherical having or nearly having the shape of a sphere; rounded; globular. [3 definitions]
spheroid a flattened sphere created by revolving an ellipse about one of its axes.
sphincter a circular band of muscle that surrounds a body opening or passage and can constrict or close it.
sphinx in Egyptian mythology, a creature with a lion's body and the head of a human or animal. [4 definitions]
sphygmomanometer an instrument that measures blood pressure in the arteries.
spic (offensive slang) a person of Hispanic descent.
Spica a blue-white star in the constellation Virgo, having a magnitude of 1.0.
spic-and-span variant of spick-and-span.
spicate having spikes, esp. a plant. [3 definitions]
spice any of various edible plant substances with a distinctive aroma or taste, such as pepper or ginger, that are used to flavor or preserve food and drink. [5 definitions]
spicebush an aromatic yellow-flowered laurel of eastern North America that produces a red fruit that was formerly dried and used as a spice. [2 definitions]
spiceless combined form of spice.
spice up to make (something) more interesting or exciting by adding new things. [2 definitions]
spick-and-span perfectly clean and tidy. [2 definitions]
spicule a small needlelike body, part, or projection, such as one of the hard processes forming the skeletal elements of invertebrates such as sponges.
spicy containing strong spices, as food. [3 definitions]
spider any of various eight-legged invertebrates, related to mites and ticks, that typically spin webs in which to nest and catch their prey.
spider monkey any of several tropical American monkeys that have long spidery limbs, rudimentary or no thumbs, and a long prehensile tail.
spider plant a plant of the lily family, with long, narrow, sometimes white-streaked leaves, commonly grown as a houseplant.