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spitfire a person, esp. a girl or woman, with a quick or fiery temper. [2 definitions]
spitter one that spits saliva. [2 definitions]
spitting image (informal) an exact likeness; spit and image.
spittle saliva. [2 definitions]
spittlebug any of various insects that secrete and cover themselves with spittle in their larval stages.
spittoon a bowl, usu. large and made of metal, for spitting into; cuspidor.
spitz any of several dogs, such as the chow chow or Pomeranian, with a thick coat, erect pointed ears, and a tail that curls over the back.
splash to dash or scatter (a liquid or semiliquid). [9 definitions]
splashdown a landing on water, as of a spacecraft.
splat1 a broad, flat wood slat, as used in a chair back.
splat2 a slapping or splattering sound.
splatter to wet or soil with splashes. [3 definitions]
splay to spread or turn outward or apart; flare. [4 definitions]
splayfoot a foot that is flat and turned outward.
spleen a ductless organ on the left side near the stomach, which filters and stores blood, destroys certain worn-out red blood cells, and produces certain white blood cells of the immune system. [2 definitions]
splendid magnificent, grand, or the like; impressive. [2 definitions]
splendiferous (informal) magnificent; fine; splendid.
splendor grandeur or magnificence. [2 definitions]
splenetic of or pertaining to the spleen; splenic. [2 definitions]
splenic of, relating to, or affecting the spleen.
splice to join (pieces of film, tape, or the like) at the ends. [4 definitions]