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craze to cause insanity in; derange. [1/6 definitions]
crazy reflecting or seeming to reflect insanity. [1/7 definitions]
dementia mental illness; madness; insanity. [1/2 definitions]
lunacy mental derangement; insanity. [1/2 definitions]
madness a state of insanity. [1/3 definitions]
maniac one who suffers from mania, or from insanity generally. (No longer in scientific use.) [1/4 definitions]
syphilis a bacterial disease that can be transmitted between sexual partners or to an infant during childbirth, causing a latent infection that can affect any organ of the body or result in paralysis or insanity.