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Comprehensive
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crux an essential, basic, crucial, or pivotal point.
fulcrum that which other things are contingent upon or built around; a pivotal point or agent. [1/2 definitions]
Galápagos Islands a group of Ecuadorian islands in the Pacific Ocean about 1,000 miles off the west coast of South America, known for their large number of endemic species and their pivotal role in Charles Darwin's research.