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downer (informal) a drug that depresses or sedates, such as a barbiturate or tranquilizer. [1/2 definitions]
Librium trademark for a drug, chlordiazepoxide, used as a tranquilizer.
meprobamate a bitter white powder that is used as a tranquilizer.
PCP a powerful and dangerous drug originally intended as an animal tranquilizer but sometimes ingested by humans for its psychedelic and mood-altering effects; phenylcyclohexylpiperidine, or phencyclidine pill.
psychotropic affecting the activities of the mind, as a tranquilizer, hallucinogen, or the like.
rauwolfia an extract from the root of one of these plants, containing the alkaloid reserpine, used as a tranquilizer and sedative. [1/2 definitions]
reserpine an alkaloid obtained from the root of the rauwolfia, used in the treatment of hypertension and as a tranquilizer.
thalidomide a crystalline solid formerly used as a sedative and tranquilizer, withdrawn from the market after having been shown to cause fetal abnormalities when taken by pregnant women.