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defect to abandon a cause, political party, country, or the like, esp. in order to join another. [1/3 definitions]
desert2 to abandon and thereby be remiss in one's duties or obligations. [2/3 definitions]
despair to lose or abandon all hope concerning something (usu. fol. by "of"). [1/3 definitions]
die-hard a person who stubbornly refuses to accept defeat or change, abandon a position, or the like. [1/2 definitions]
ditch (informal) to reject or abandon (someone or something). [2/7 definitions]
forsake to abandon or desert. [1/2 definitions]
give up to surrender (something) or abandon reluctantly. [1/4 definitions]
jettison to abandon, discard, or cancel (something that is unnecessary or a hindrance). [1/4 definitions]
leave in the lurch to abandon (someone) in an embarrassing or difficult position.
life raft a small, usu. inflatable raft for use by people forced to abandon a boat or ship.
reform to cause (someone) to abandon an evil, corrupt, or irresponsible way of living. [1/5 definitions]
rip3 (informal) a person living in abandon or debauchery; reprobate.
scuttle3 to give up; discard; abandon. [1/4 definitions]
shift to remove or abandon and replace with another; change. [1/12 definitions]
surrender to abandon or relinquish (an intention, desire, or the like). [1/5 definitions]
tergiversate to change or abandon what one has believed, advocated, or practiced; become a renegade. [1/2 definitions]
turn one's back on to neglect or abandon.
walk out to abandon someone despite one's responsibilities or commitments (usu. fol. by "on"). [1/4 definitions]