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abandon ship to extricate oneself from a situation where danger or failure seems imminent, often at the expense of loyalty to a group or cause. [1/2 definitions]
abort of a program or operation, to end prematurely, usu. in failure. [1/6 definitions]
abortion a project or idea that has failed to be carried to completion, or the result of the failure to reach completion. [1/4 definitions]
Addison's disease a disease caused by disturbance or failure of the adrenal glands, resulting in anemia, low blood pressure, weakness, and an abnormal brownish tinge to the skin.
anuresis partial or total failure of the kidneys to produce and secrete urine, or blockage which inhibits normal urine excretion.
bankruptcy a condition of utter failure, ruin, or lack. [1/2 definitions]
blackout the extinguishing or hiding of all the lights of a city or region, as in a power failure or air raid. [1/4 definitions]
bloodbath (informal) a period or instance of great loss, failure, or disappointment. [1/2 definitions]
blunder to make a mess or a failure of. [1/5 definitions]
bomb (informal) a failure. [1/8 definitions]
buoyant able to avoid downfall or failure. [1/3 definitions]
cardiac arrest the failure of the heart to pump blood; heart attack.
chagrin embarrassment or humiliation arising from disappointment or failure. [1/2 definitions]
Cinderella anyone who achieves sudden success or happiness after a period of failure or misery. [1/2 definitions]
clinker2 (informal) a total failure; unsatisfactory product. [1/2 definitions]
close call (informal) a narrow escape from danger, failure, detection, or the like.
come a cropper (informal) to suffer a failure or fiasco. [1/2 definitions]
cook one's goose (informal) to cause one to lose further opportunity; ruin one's chances; doom one to failure or defeat.
coronary insufficiency a medical condition in which the heart muscle does not receive enough oxygenated blood, resulting in angina pectoris or heart failure.
crash1 the sudden failure of a financial or other enterprise, or of the economy in general. [1/17 definitions]
damn to cause the failure of; ruin. [1/11 definitions]