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bovine spongiform encephalopathy a fatal disease, also known as "mad cow disease," that affects the nervous system of cattle.
demented mentally disturbed; mad; insane. [1/2 definitions]
demoniac apparently under the influence of a demon or evil spirit; raging; mad. [1/3 definitions]
insane having a disabling mental disease; crazy; mad. [1/4 definitions]
loco (slang) crazy; mad; insane. [1/3 definitions]
madden to cause to become insane; drive mad. [2/3 definitions]
madder2 comparative of mad.
maddest superlative of mad.
prion any infectious agent composed of misfolded protein, such as the misfolded protein that causes "mad cow disease."