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melamine a white crystalline solid, used in the manufacture of resins.
melancholia a mental illness characterized by depression and withdrawal.
melancholic suffering or inclined to suffer from melancholy; sad, gloomy, or depressed. [2 definitions]
melancholy a sad, gloomy, or depressed state or quality. [3 definitions]
Melanesia one of the three principal Pacific island groups, south of the equator, stretching from northeast of New Guinea to Fiji. (Cf. Micronesia, Polynesia.)
Melanesian of or pertaining to Melanesia or its people, cultures, languages, or the like. [3 definitions]
mélange a mixture, usu. of very dissimilar elements.
melanin a dark pigment that colors the skin, hair, and other tissue of humans and some animals.
melanism an esp. high amount of dark pigmentation, as in hair, skin, feathers, or the like. [2 definitions]
melano- dark; black.
melanocyte an epidermal cell in birds and mammals that produces and stores the pigment melanin.
melanoma a malignant tumor, esp. of the skin or eye, that is darkly pigmented with melanin.
melatonin a hormone secreted by the pineal gland that is important in regulating the body's response to biological rhythms such as the light-dark cycle.
Melba toast a very thinly sliced and crisply toasted piece of bread.
meld1 to declare and show (one's hand) in certain card games, such as pinochle. [2 definitions]
meld2 to blend or merge.
melee a chaotic hand-to-hand fight among several combatants; free-for-all. [2 definitions]
meliorate to make or become better; improve; ameliorate.
melioration improvement; amelioration. [2 definitions]
melisma a succession of different notes sung to one syllable in plainsong and in certain Asian and Near Eastern music.
mellifluous flowing and sweet, as though with honey.