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degenerate to decline from an original or former condition; change for the worse in nature or quality; deteriorate. [1/6 definitions]
go to seed to lose one's energy or vitality; deteriorate. [1/2 definitions]
go to the dogs (informal) to seriously decline or deteriorate; degenerate.
retinitis pigmentosa an inherited, incurable disease of the eye in which the retina and optic nerve gradually deteriorate, resulting in total blindness.
rot to deteriorate or become damaged, unsafe, or useless (often fol. by "away," through," or the like). [1/12 definitions]
slumlord an owner of shabby rental property who charges high rents and allows the buildings to deteriorate.
slump to deteriorate or fall off, esp. quickly. [1/6 definitions]
wear to deteriorate or sustain damage through prolonged use or friction. [1/15 definitions]
weather to discolor, deteriorate, or harm by exposing to weather. [1/7 definitions]