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Comprehensive
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disability the condition or state of incapacity, esp. as caused by an injury, congenital defect, illness, or the like. [2/3 definitions]
inefficacy incapacity for producing the desired result; ineffectiveness.
vice president (caps.) the elected official of this rank in the U.S. government, who serves as president of the Senate and succeeds the President in the event of the latter's death, removal, incapacity, or the like. [1/3 definitions]